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105816-06-6

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105816-06-6 Structure

105816-06-6 Structure
IdentificationBack Directory
[Name]

D-Phenylalanine, N-[[4-(1-methylethyl)cyclohexyl]carbonyl]-, cis-
[CAS]

105816-06-6
[Synonyms]

Nateglinide EP Impurity C
Nateglinide Related CoMpound C
Nateglinide Impurity 6 (Nateglinide EP Impurity C)
N-(cis-4-isopropylcyclohexanecarbonyl)-D-phenylalanine
N-[(cis-4-Isopropylcyclohexyl)carbonyl]-D-phenylalanine
N-[[cis-4-(1-Methylethyl)cyclohexyl]carbonyl]-D-phenylalanine
cis-N-[[4-(1-Methylethyl)cyclohexyl]carbonyl]-D-phenylalanine
D-Phenylalanine, N-[[4-(1-methylethyl)cyclohexyl]carbonyl]-, cis-
D-Phenylalanine, N-[[cis-4-(1-methylethyl)cyclohexyl]carbonyl]- (9CI)
N-[[cis-4-(1-Methylethyl)cyclohexyl]carbonyl]-D-phenylalanine (Nateglinide IMpurity)
Nateglinide Impurit Ⅱ :N-[[cis-4-(1-Methylethyl)cyclohexyl]carbonyl]-D-phenylalanine
Nateglinide Impurit Ⅱ :N-[[cis-4-(1-Methylethyl)cyclohexyl]carbonyl]-D-phenylalanine
Nateglinide Related Compound C (5 mg) (N-(cis-4-isopropylcyclohexanecarbonyl)-D-phenylalanine)
Nateglinide Related Compound C (N-(cis-4-isopropylcyclohexanecarbonyl)-D-phenylalanine) (1457630)
[Molecular Formula]

C19H27NO3
[MDL Number]

MFCD21606974
[MOL File]

105816-06-6.mol
[Molecular Weight]

317.42
Chemical PropertiesBack Directory
[Boiling point ]

527.6±39.0 °C(Predicted)
[density ]

1.104±0.06 g/cm3(Predicted)
[form ]

neat
[pka]

3.61±0.10(Predicted)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26
[HS Code ]

2924296000
Hazard InformationBack Directory
[Uses]

N-[[cis-4-(1-Methylethyl)cyclohexyl]carbonyl]-D-phenylalanine, is an impurity of Nateglinide (N379375), which is an amino-acid derivative that stimulates insulin secretion, and used as an antidiabetic. Nateglinide USP Related Compound C.
[Definition]

ChEBI: Nateglinide is an N-acyl-D-phenylalanine resulting from the formal condensation of the amino group of D-phenylalanine with the carboxy group of trans-4-isopropylcyclohexanecarboxylic acid. An orally-administered, rapidly-absorbed, short-acting insulinotropic agent, it is used for the treatment of type 2 diabetes mellitus. It has a role as an EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor and a hypoglycemic agent.
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