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105925-39-1

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105925-39-1 Structure

105925-39-1 Structure
IdentificationBack Directory
[Name]

Tubulin inhibitor 6
[CAS]

105925-39-1
[Synonyms]

iHAP1
Tubulin inhibitor 6
Methanone, (2-chloro-10H-phenothiazin-10-yl)(4-methoxyphenyl)-
[Molecular Formula]

C20H14ClNO2S
[MOL File]

105925-39-1.mol
[Molecular Weight]

367.85
Chemical PropertiesBack Directory
[Melting point ]

155-157 °C
[Boiling point ]

549.1±50.0 °C(Predicted)
[density ]

1.364±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: 62.5 mg/mL (169.91 mM)
[form ]

A crystalline solid
[pka]

-5.56±0.20(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H319-H335-H315
[Precautionary statements ]

P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501
Hazard InformationBack Directory
[Biological Activity]

Tubulin inhibitor 6 is an activator of protein phosphatase 2A (PP2A) enzymes that activates PP2A-B56ε and efficiently kills malignant cells.
[in vitro]

Tubulin inhibitor 6 displays submicromolar antiproliferative activity.

[target]

TargetValue
PP2A
()
[storage]

Store at -20°C
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