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105955-10-0

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105955-10-0 Structure

105955-10-0 Structure
IdentificationBack Directory
[Name]

N-[2-(3,4-DIHYDROXYPHENYL)ETHYL]OCTADECANAMIDE
[CAS]

105955-10-0
[Synonyms]

STEARDA
N-[2-(3,4-DIHYDROXYPHENYL)ETHYL]OCTADECANAMIDE
Octadecanamide, N-[2-(3,4-dihydroxyphenyl)ethyl]-
[Molecular Formula]

C26H45NO3
[MDL Number]

MFCD08703100
[MOL File]

105955-10-0.mol
[Molecular Weight]

419.64
Chemical PropertiesBack Directory
[storage temp. ]

Store at +4°C
[solubility ]

Soluble to 5 mM in ethanol with gentle warming
[form ]

Powder
Hazard InformationBack Directory
[Uses]

STEARDA is a novel, endogenous capsaicin-like lipid that produces hyperalgesia.
[Definition]

ChEBI: N-stearoyl dopamine is a carboxamide. It is functionally related to a dopamine.
[Biological Activity]

Endogenous fatty acid dopamide that displays 'entourage' effects on endovanilloids NADA and anandamide. Inactive at TRPV1 and CB 1 receptors (at concentrations up to 5 μ M) and does not inhibit AMT or FAAH (IC 50 > 25 μ M). However, potentiates TRPV1-mediated effects of NADA in vitro and in vivo ; enhances effects on intracellular Ca 2+ (EC 50 lowered 3-fold) and nociception. Also inhibits arachidonate 5-lipoxygenase (IC 50 = 16 nM).
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