| Identification | Back Directory | [Name]
SENKTIDE | [CAS]
106128-89-6 | [Synonyms]
SENKTIDE
succinyl(asp6
Senktide?, BR
SENKTIDE (6-11)
SUC-DF(ME)FGLM-NH2
SUC-DF-(NMEF)-GLM-NH2
M.W. 842.1 C40H55N7O11S
Senktide trifluoroacetate salt
Suc-[Asp6,MePhe8]substance P(6-11)
[SUCCINYL-ASP6,ME-PHE8] SUBSTANCE P
SUC-ASP-PHE-N-ME-PHE-GLY-LEU-MET-NH2
SUCCINYL-ASP-PHE-ME-PHE-GLY-LEU-MET-NH2
SELECTIVE NEUROKININ B RECEPTOR PEPTIDE
SUC-[ASP6, N-ME-PHE8]-SUBSTANCE P (6-11)
SUCCINYL-ASP-PHE-(N-ME)PHE-GLY-LEU-MET-NH2
Succinyl-6-Asp-8-me-Phe-substance p (6-11)
SUCCINYL-(ASP6,N-ME-PHE8)-SUBSTANCE P (6-11)
SUCCINYL-ASP-PHE-N-METHYL-PHE-GLY-LEU-MET-NH2
Substance p (6-11), succinyl-Asp(6)-me-Phe(8)-
Substance P, fragment 6-11, succinyl[Asp6, NMePhe8]
SUBSTANCE P SUCCINYL-[ASP6, N-ME-PHE8]-FRAGMENT 6-11
[SUCCINYL-ASP6,N-ME-PHE8]-SUBSTANCE P, FRAGMENT 6-11
Suc-Asp-Phe-MePhe-Gly-Leu-Met-NH2 trifluoroacetate salt
[SUCCINYL-ASP6 N-ME-PHE8]-SUBSTANCE P (6-11) (SENKTIDE)
Substance p (6-11), succinyl-aspartyl(6)-methylphenylalanine(8)-
N-(3-Carboxy-1-oxopropyl)-L-Asp-L-Phe-N-methyl-L-Phe-Gly-L-Leu-L-Met-NH2
N-(3-Carboxy-1-oxopropyl)-L-αAsp-L-Phe-N-methyl-L-Phe-Gly-L-Leu-L-Met-NH2
N-(3-Carboxy-1-oxopropyl)-6-(N-methyl-L-phenylalanine)-7-de-L-valine-4-10-neuromedin B (swine spinal cord)
DFFGLM (Modifications: Asp-1 = Succinyl-Asp, Phe-3 = Me-Phe, Met-6 = C-terminal amide) trifluoroacetate salt
4-10-Neuromedin B (swine spinal cord), N-(3-carboxy-1-oxopropyl)-6-(N-methyl-L-phenylalanine)-7-de-L-valine-
L-Methioninamide, N-(3-carboxy-1-oxopropyl)-L-α-aspartyl-L-phenylalanyl-N-methyl-L-phenylalanylglycyl-L-leucyl-
L-Methioninamide, N-(3-carboxy-1-oxopropyl)-L-alpha-aspartyl-L-phenylalanyl-N-methyl-L-phenylalanylglycyl-L-leucyl- | [Molecular Formula]
C40H55N7O11S | [MDL Number]
MFCD00076799 | [MOL File]
106128-89-6.mol | [Molecular Weight]
841.97 |
| Chemical Properties | Back Directory | [Boiling point ]
1262.6±65.0 °C(Predicted) | [density ]
1.290±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
DMSO : 50 mg/mL (59.38 mM; Need ultrasonic) | [form ]
film | [pka]
4.23±0.10(Predicted) | [color ]
colorless |
| Hazard Information | Back Directory | [Uses]
Senktide is a potent, selective agonist of the neuromedin K3 (NK3) receptor (EC50 = 0.5-3 nM). It less potently agonizes the NK1 receptor (EC50 = 35 μM) and is without effect on the NK2 receptor. Senktide is used to study the action of the NK3 receptor in cells and in animals. | [storage]
Desiccate at -20°C |
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