ChemicalBook--->CAS DataBase List--->107430-66-0

107430-66-0

107430-66-0 Structure

107430-66-0 Structure
IdentificationBack Directory
[Name]

CD1530
[CAS]

107430-66-0
[Synonyms]

CD1530
CD1530 >=98% (HPLC)
4-(6-Hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)benzoicacid
Benzoic acid, 4-(6-hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)-
[Molecular Formula]

C27H26O3
[MDL Number]

MFCD09263615
[MOL File]

107430-66-0.mol
[Molecular Weight]

398.49
Chemical PropertiesBack Directory
[Boiling point ]

610.7±55.0 °C(Predicted)
[density ]

1.290±0.06 g/cm3(Predicted)
[storage temp. ]

Store at +4°C
[solubility ]

50 mM in 1 eq. NaOH: Soluble
[form ]

powder
[pka]

4.13±0.10(Predicted)
[color ]

white to beige
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P305+P351+P338
Hazard InformationBack Directory
[Uses]

CD 1530 is a retinoic acid receptor γ selective agonist. In combination with bexxarotene, they inhibit murine oral-cavity carcinogensis. It is found to inhibit heterotopic ossification and preserve tendon stem cell characteristics. It is also associated with RAR signalling in asthma.
[Biological Activity]

Potent and selective RAR γ receptor agonist (K i values are 150, 1500 and 2750 nM for RAR γ , RAR β and RAR α receptors respectively). Activates transcriptional activity (AC 50 = 1.8 nM).
[storage]

Store at +4°C
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