Identification | Back Directory | [Name]
CD1530 | [CAS]
107430-66-0 | [Synonyms]
CD1530 CD1530 >=98% (HPLC) 4-(6-Hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)benzoicacid Benzoic acid, 4-(6-hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)- | [Molecular Formula]
C27H26O3 | [MDL Number]
MFCD09263615 | [MOL File]
107430-66-0.mol | [Molecular Weight]
398.49 |
Chemical Properties | Back Directory | [Boiling point ]
610.7±55.0 °C(Predicted) | [density ]
1.290±0.06 g/cm3(Predicted) | [storage temp. ]
Store at +4°C | [solubility ]
50 mM in 1 eq. NaOH: Soluble | [form ]
powder | [pka]
4.13±0.10(Predicted) | [color ]
white to beige |
Hazard Information | Back Directory | [Uses]
CD 1530 is a retinoic acid receptor γ selective agonist. In combination with bexxarotene, they inhibit murine oral-cavity carcinogensis. It is found to inhibit heterotopic ossification and preserve tendon stem cell characteristics. It is also associated with RAR signalling in asthma. | [Biological Activity]
Potent and selective RAR γ receptor agonist (K i values are 150, 1500 and 2750 nM for RAR γ , RAR β and RAR α receptors respectively). Activates transcriptional activity (AC 50 = 1.8 nM). | [storage]
Store at +4°C |
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Company Name: |
Energy Chemical
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Tel: |
021-58432009 400-005-6266 |
Website: |
http://www.energy-chemical.com |
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