| Identification | Back Directory | [Name]
Gly-Pro-Leu-Gly-Ile-Ala-Gly-Gln | [CAS]
109053-09-0 | [Synonyms]
Gly-Pro-Leu-Gly-Ile-Ala-Gly-Gln
L-Glutamine, glycyl-L-prolyl-L-leucylglycyl-L-isoleucyl-L-alanylglycyl- | [Molecular Formula]
C31H53N9O10 | [MDL Number]
MFCD30602097 | [MOL File]
109053-09-0.mol | [Molecular Weight]
711.81 |
| Hazard Information | Back Directory | [Biological Activity]
Gly-Pro-Leu-Gly-Ile-Ala-Gly-Gln（GPLGIAGQ）, an MMP2 cleavable polypeptide, has been used as a stimulus-sensitive linker in both liposomes and micellar nanocarriers for MMP2-triggered tumor targeting studies. GPLGIAGQ can be used to synthesize unique MMP2-targeted photosensitizers in photodynamic therapy (PDT). | [in vitro]
GPLGIAGQ is used to trigger PEG deshielding of liposomal carriers, resulting in enhanced cellular internalization. |
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