| Identification | Back Directory | [Name]
SK 609 | [CAS]
1092797-77-7 | [Synonyms]
SK 609
SK609 HCl
SK609 hydrochloride
SK-609 hydrochloride
SK 609 hydrochloride
SK609 hydrochloride (ES609)
SK609 hydrochloride >=98% (HPLC) | [Molecular Formula]
C10H15Cl2N | [MOL File]
1092797-77-7.mol | [Molecular Weight]
220.14 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [color ]
Off-white to light brown | [Water Solubility ]
H2O: 2mg/mL, clear |
| Hazard Information | Back Directory | [Biological Activity]
SK609 (ES609) is a Dopamine D3 receptor (D3R) selective agonist with a bias towards the G-protein-dependent pathway rather than recruiting β-arrestin-2 and an EC50 value of 113.9 nM for activation of ERK1/2 phosphorylation. SK609 has been shown to reverse akinesia and reduce L-dopa-induced dyskinesia in a hemiparkinsonian r at model of Parkinsonμs desease. It does not induce desensitization of D3R. | [storage]
Store at -20°C |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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