| Identification | Back Directory | [Name]
Boc-Leu-Arg-Arg-AMC . 2 HCl | [CAS]
109358-46-5 | [Synonyms]
Boc-LRR-AMC
Boc-Leu-Arg-Arg-AMC . 2 HCl
N-[(1,1-Dimethylethoxy)carbonyl]-L-leucyl-L-arginyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-argininamide
tert-butyl N-[(2S)-1-[[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-(4-methyl-2-oxochromen-7-yl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate | [Molecular Formula]
C33H52N10O7 | [MDL Number]
MFCD00133639 | [MOL File]
109358-46-5.mol | [Molecular Weight]
700.83 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
White to Off-White | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Description]
Boc-LRR-AMC is a fluorogenic substrate for the trypsin-like activity of the 26S proteasome or 20S proteolytic core. Upon enzymatic cleavage by the 26S proteasome or 20S proteolytic core, amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify 26S proteasome or 20S proteolytic core trypsin-like activity. AMC displays excitatioemission maxima of 340-360/440-460 nm, respectively. | [Uses]
Boc-Leu-Arg-Arg-AMC Dihydrochloride is a useful research chemical compound used as a fluorogenic peptide substrate in the inhibition of 26S proteasomes. | [storage]
Store at -20°C |
|
|