ChemicalBook--->CAS DataBase List--->1094250-15-3

1094250-15-3

1094250-15-3 Structure

1094250-15-3 Structure
IdentificationBack Directory
[Name]

Englerin A
[CAS]

1094250-15-3
[Synonyms]

Englerin A
(-)-ENGLERIN A
(?)-Englerin A
Englerin A high purity
(1S,2R,5R,6R,7S,8R,10R)-10-(Glycoloyloxy)-8-isopropyl-1,5-dimethyl-11-oxatricyclo[6.2.1.02,6]undec-7-yl(2E)-3-phenylacrylate
2-Propenoic acid, 3-phenyl-, (1R,3aR,4S,5R,7R,8S,8aR)-decahydro-5-[(2-hydroxyacetyl)oxy]-1,4-dimethyl-7-(1-methylethyl)-4,7-epoxyazulen-8-yl ester, (2E)-
[Molecular Formula]

C26H34O6
[MDL Number]

MFCD32068367
[MOL File]

1094250-15-3.mol
[Molecular Weight]

442.54
Chemical PropertiesBack Directory
[Boiling point ]

550.3±50.0 °C(Predicted)
[density ]

1.20±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[form ]

Solid
[pka]

12.88±0.10(Predicted)
[color ]

White to light yellow
Hazard InformationBack Directory
[Uses]

Englerin A is a selective inhibitor of renal cancer cell growth.
[Definition]

ChEBI: Englerin A is a guaiane sesquiterpenoid that is isolated from the bark of Phyllanthus engleri, a plant native to Tanzania and Zimbabwe. It acts as a potent and specific inhibitor of renal cancer cell growth. It has a role as a metabolite and an antineoplastic agent. It is a guaiane sesquiterpenoid, a cinnamate ester and a glycolate ester.
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