Identification | Back Directory | [Name]
Dehydrocurvularin, 10,11- | [CAS]
1095588-70-7 | [Synonyms]
10,11-Dehydrocurvularin Dehydrocurvularin, 10,11- (R)-10,11-Dehydrocurvularin 2H-3-Benzoxacyclododecin-2,10(1H)-dione, 4,5,6,7-tetrahydro-11,13-dihydroxy-4-methyl-, (4R,8E)- | [Molecular Formula]
C16H18O5 | [MDL Number]
MFCD09752720 | [MOL File]
1095588-70-7.mol | [Molecular Weight]
290.31 |
Chemical Properties | Back Directory | [Melting point ]
>213°C (dec.) | [storage temp. ]
-20°C Freezer | [solubility ]
DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
Off-White to Pale Beige |
Hazard Information | Back Directory | [Uses]
Dehydrocurvularin is a 12-membered macrocyclic lactone incorporating a resorcinyl moiety, produced by a number of fungal species including Curvularia, Penicillium and Alternaria. Dehydrocurvularin inhibits cell division by disrupting mitotic spindle formation and acts as a developmental regulator by inhibiting self-sporulation in Alternaria alternata. More recently dehydrocurvularin has been shown to have antimalarial activity. | [storage]
+4°C |
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