| Identification | Back Directory | [Name]
Ristocetin | [CAS]
11021-66-2 | [Synonyms]
Ristomycin A
Ristocetin, RistoMycin III, Spontin, Riston | [Molecular Formula]
C95H110N8O44 | [MDL Number]
MFCD01684599 | [MOL File]
11021-66-2.mol | [Molecular Weight]
2067.92 |
| Safety Data | Back Directory | [RIDADR ]
3249 | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [Toxicity]
mouse,LD50,intravenous,1350mg/kg (1350mg/kg),SKIN AND APPENDAGES (SKIN): PRIMARY IRRITATION: AFTER TOPICAL EXPOSURE,"Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds., Tokyo, Univ. of Tokyo Press, 1967Vol. -, Pg. 568, 1967. |
| Hazard Information | Back Directory | [Uses]
Ristocetin A sulfate is a potent antibacterial glycopeptide antibiotic that was withdrawn from clinical use following a high incidence of thrombocytopenia. Further investigation found that ristocetin A induced platelet aggregation by binding to a factor absent in people suffering from von Willebrand's disease, leading to the use of ristocetin A as an important diagnostic aid. |
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