Identification | Back Directory | [Name]
DIHYDROERGOTAMINE MESYLATE | [CAS]
11032-41-0 | [Synonyms]
DCCK DHETX dihydroergotoxin dihydro-ergotoxin Dihydroergotoxine 9,10-Dihydroergotoxine DIHYDROERGOTAMINE MESYLATE Ergotoxine, dihydro- (8CI, 9CI) DIHYDROERGOTAMINE METHANESULFONATE DIHYDROERGOTAMINE METHANESULFONATE SALT Indolo[4,3-fg]quinoline, ergotoxine deriv. 8H-Oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine, ergotoxine deriv. 9,10-DIHYDRO-12'-HYDROXY-2'-METHYL-5'-(PHENYLMETHYL)ERGOTAMAN-3',6',18-TRIONE MESYLATE | [Molecular Formula]
C34H41N5O8S | [MDL Number]
MFCD00058615 | [MOL File]
11032-41-0.mol | [Molecular Weight]
679.78 |
Hazard Information | Back Directory | [Originator]
Redergin,Lek | [Uses]
Cognition adjuvant. | [Manufacturing Process]
Dihydrotoxine is a mixture of three hydrogenated alkaloides of ergot spur.
(Claviceps purpurea). 10 g ergotoxine (the mixture of ergocornine,
ergocristine, ergocryptine 1:1:1) in 200 ml dioxane and 20 g Pd/BaSO4 were
stirred at a H2 pressure 10 atmospheres at 80°C for 5 hours. The catalyst was
filtered off, a filtrate was distilled to dryness in vacuum. The residue was in
chloroform dissolved and shook with aluminum oxide. The Al2O3 was filtered
off, the filtrate was crystallized after adding of hot benzene and cooling. Yield
6-8 g dihydroergotoxine. It crystallized with 1 mol of benzene. MP: 185°C. | [Brand name]
Alkergot (Sandoz); Circanol(3M Pharmaceuticals); Deapril (Bristol-Myers Squibb);Gerimal (Watson); Hydergine (Novartis). | [Therapeutic Function]
Vasodilator |
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