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110351-92-3

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110351-92-3 Structure

110351-92-3 Structure
IdentificationBack Directory
[Name]

20R-Camptothecin
[CAS]

110351-92-3
[Synonyms]

(R)-Camptothecin
20R-Camptothecin
(R)-(-)-Camptothecin
(R)-(-)-Camptothecine
Irinotecan Impurity 42
Camptothecin Impurity 6
Irinotecan Impurity 19 HCl
Irinotecan Hydroxyl Acid 19
(R)-4-Ethyl-4-hydroxy-1H-pyrano[3’,4’:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
(4R)-4β-Ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-, (4R)-
[Molecular Formula]

C20H16N2O4
[MOL File]

110351-92-3.mol
[Molecular Weight]

348.35
Chemical PropertiesBack Directory
[Boiling point ]

757.0±60.0 °C(Predicted)
[density ]

1.51±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[pka]

11.24±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

Antitumor alkaloid. Binds irreversible to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA. A cytotoxic antitumor agent
[Uses]

Antitumor alkaloid. Binds irreversible to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA. A cytotoxic antitumor agent.
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