| Hazard Information | Back Directory | [Definition]
ChEBI: SN-38 is a member of the class of pyranoindolizinoquinolines that is (4S)-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione bearing two additional ethyl substituents at positions 4 and 11 as well as two additional hydroxy substituents at positions 4 and 9. It is the active metabolite of irinotecan and is ~1000 times more active than irinotecan itself. It has a role as an apoptosis inducer, an EC 5.99.1.2 (DNA topoisomerase) inhibitor, a drug metabolite and an antineoplastic agent. It is a pyranoindolizinoquinoline, a delta-lactone, a tertiary alcohol and a member of phenols. |
|
| Company Name: |
Ralington Pharma
|
| Tel: |
+91-7948911722 +91-9687771722 |
| Website: |
www.ralingtonpharma.com |
| Company Name: |
Laurus Labs Ltd
|
| Tel: |
+91-4066594333 +91-4039804333 |
| Website: |
www.lauruslabs.com |
| Company Name: |
Raising Sun Pharma
|
| Tel: |
+91-9399941155 +91-9399941155 |
| Website: |
www.raisingsunpharma.com |
|