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1112994-35-0

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1112994-35-0 Structure

1112994-35-0 Structure
IdentificationBack Directory
[Name]

P 2281
[CAS]

1112994-35-0
[Synonyms]

P2281
P-2281
P 2281
[Molecular Formula]

C9H8ClN3O
[MDL Number]

MFCD24392542
[MOL File]

1112994-35-0.mol
[Molecular Weight]

209.63
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

P-2281 is a mTOR inhibitor and is efficacious in a murine model of human colitis. In the dextran sulfate sodium (DSS) model of colitis, macroscopic colon observations demonstrated that P2281 significantly inhibited DSS-induced weight loss, improved rectal bleeding index, decreased disease activity index, and reversed DSS-induced shortening of the colon.
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