ChemicalBook--->CAS DataBase List--->1114-81-4

1114-81-4

1114-81-4 Structure

1114-81-4 Structure
IdentificationBack Directory
[Name]

O-PHOSPHO-L-THREONINE
[CAS]

1114-81-4
[Synonyms]

H-THR(PO3H2)-OH
O-Phosphothreonine
Threonine phosphate
O-PHOSPHO-L-THREONINE
L-THREONINE O-PHOSPHATE
Oxo-Phospho-L-Threonine
L-Threonine, O-phosphono-
(2S,3R)-O-Phosphothreonine
threoninium dihydrogen phosphate
L-Threonine dihydrogen phosphate
PHLOROGLUCINOL CARBOXYLIC ACID(RG)
PHOSPHOTHREONINE ANTIBODY INHIBITOR
(2S,3R)-2-Amino-3-phosphonooxybutanoic acid
L-2-AMINO-3-HYDROXYBUTANOIC ACID 3-PHOSPHATE
(s)-2-amino-3-hydroxybutanoic acid 3-phosphate
Phosphoric acid dihydrogen (1S,2R)-1-amino-1-carboxypropan-2-yl ester
L-Threonine O-phosphate, (S)-2-Amino-3-hydroxybutanoic acid 3-phosphate
[EINECS(EC#)]

214-217-5
[Molecular Formula]

C4H10NO6P
[MDL Number]

MFCD00069578
[MOL File]

1114-81-4.mol
[Molecular Weight]

199.1
Chemical PropertiesBack Directory
[Melting point ]

169 °C
[Boiling point ]

454.0±55.0 °C(Predicted)
[density ]

1.671±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C
[solubility ]

NH4OH 1 M: 0.1 g/mL, clear, colorless
[form ]

A solid
[pka]

1.73±0.10(Predicted)
[color ]

white
[BRN ]

1727078
Safety DataBack Directory
[WGK Germany ]

3
[F ]

10
Hazard InformationBack Directory
[Definition]

ChEBI: O-phospho-L-threonine is a L-threonine derivative phosphorylated at the side-chain hydroxy function. It has a role as an Escherichia coli metabolite. It is a L-threonine derivative, a non-proteinogenic L-alpha-amino acid and an O-phosphoamino acid. It is a conjugate acid of an O-phosphonato-L-threonine(2-).
[Biochem/physiol Actions]

O-Phospho-L-threonine is an amino acid derivative.
[Purification Methods]

Dissolve the phosphate in the minimum volume of H2O, add charcoal, stir for a few minutes, filter and apply onto a column of Dowex 50W (H+ form), then elute with 2N HCl. Evaporate the eluates under reduced pressure whereby the desired fraction produces crystals of the phosphate which can be recrystallised from H2O/MeOH mixtures and the crystals are then dried in vacuo over P2O5 at ~80o. [de Verdier Acta Chem Scand 7 196 1953, Beilstein 4 IV 3175.]
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