Log in | Join Free | china | japan | germany
ChemicalBook--->CAS DataBase List--->111686-79-4

111686-79-4

Request For Quotation
111686-79-4 Structure

111686-79-4 Structure
IdentificationBack Directory
[Name]

2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE
[CAS]

111686-79-4
[Synonyms]

fpl12924aa
pr934-423a
RemacemideHCl
REMACEMIDE HYDROCHLORIDE
2-AMino-N-(1,2-diphenylpropan-2-yl)acetaMide hydrochloride
2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE
2-diphenylethyl)acetamidemonohydrochloride(+-)-2-amino-n-(1-methyl-
2-amino-n-(1-methyl-1,2-diphenylethyl)-,monohydrochloride,(+-)-acetamid
[Molecular Formula]

C17H21ClN2O
[MDL Number]

MFCD00882179
[MOL File]

111686-79-4.mol
[Molecular Weight]

304.81
Chemical PropertiesBack Directory
[Melting point ]

253-254°
[storage temp. ]

room temp
[solubility ]

H2O: >10mg/mL
[form ]

powder
[color ]

white to beige
[Water Solubility ]

Soluble to 100 mM in water
Safety DataBack Directory
[Hazard Codes ]

Xn,N
[Risk Statements ]

22-41-50/53
[Safety Statements ]

26-39-45-60-61
[RIDADR ]

UN 3077 9 / PGIII
[WGK Germany ]

3
[RTECS ]

AB4349500
[Toxicity]

LD50 (calculated as base) in rats (mg/kg): ~50 i.v., ~900 orally (Muir, Palmer)
Hazard InformationBack Directory
[Uses]

Anticonvulsant (neuroprotective).
[Biological Activity]

Non-competitive NMDA receptor antagonist; blocks ion channel and allosteric modulatory site (IC 50 = 8-68 mM). Anticonvulsant in vivo and metabolizes to a more potent desglycine analog. Weakly blocks voltage-dependent Na + channels (IC 50 = 161 mM).
[Biochem/physiol Actions]

Remacemide HCl is a low affinity NMDA antagonist with anticonvulsant properties. Remacemide also been shown to block voltage-dependent sodium channels.
[storage]

Desiccate at RT
111686-79-4 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000 , +1-00000000000
Website: https://www.targetmol.com/
Company Name: Aromsyn Co., Ltd.
Tel: +86-0571-85585865 +8613336024896 , +8613336024896
Website: https://www.aromsyn.com/
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525 , +8618327326525
Website: topule.com/
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Website: www.aladdinsci.com/
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 821-50328103-801 18930552037
Website: https://www.chemicalbook.com/ShowSupplierProductsList13285/0.htm
Company Name: SynAsst Chemical.  
Tel: 021-60343070
Website: www.chemicalbook.com/ShowSupplierProductsList15848/0.htm
Company Name: Sigma-Aldrich  
Tel: 021-61415566 800-8193336
Website: https://www.sigmaaldrich.cn
Company Name: EMMX Biotechnology LLC  
Tel: 888-539-0666
Website: www.emmx.com
Company Name: Energy Chemical  
Tel: 021-58432009 400-005-6266
Website: http://www.energy-chemical.com
Company Name: MedBioPharmaceutical Technology Inc  
Tel: 021-69568360 18916172912
Website: http://www.med-bio.cn/
Company Name: Wuhan Topule  
Tel: +86-02787215551 +86-19945035818
Website: http://www.topule.com/
Company Name: Changzhou Furuisi Biotechnology Co., Ltd  
Tel: 0519-85524369
Website: www.chemicalbook.com/ShowSupplierProductsList1441214/0.htm
Company Name: Beijing Jin Ming Biotechnology Co., Ltd.  
Tel: 010-60605840 15801484223;
Website: http://www.jm-bio.com/
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310
Website: https://www.targetmol.cn/
Company Name: Shanghai Tachizaki Biomedical Research Center  
Tel: 18014399201
Website: http://www.chemlab-tachizaki.com/
Company Name: ApexBio Technology  
Tel: + 1-832-696-8203
Website: www.apexbt.com
Company Name: Pharma Affiliates  
Tel: 172-5066494
Website: https://www.chemicalbook.com/ShowSupplierProductsList694812/0.htm
Company Name: Pharmaffiliates Analytics and Synthetics P. Ltd  
Tel: +91-172-5066494
Website: www.pharmaffiliates.com
Tags:111686-79-4 Related Product Information