ChemicalBook--->CAS DataBase List--->112190-24-6

112190-24-6

112190-24-6 Structure

112190-24-6 Structure
IdentificationBack Directory
[Name]

U 75875
[CAS]

112190-24-6
[Synonyms]

U 75875
PNU-75875
N-(1-Naphtyloxyacetyl)-L-His-[(2R,3R,4R,5S)-3,4-dihydroxy-2-isopropyl-5-(cyclohexylmethyl)-5-amino*pentanoyl]-L-Ile-(2-pyridylmethyl)NH2
(2R,3R,4R,5S)-6-cyclohexyl-3,4-dihydroxy-5-[[(2S)-3-(1H-imidazol-5-yl)-2-[(2-naphthalen-1-yloxyacetyl)amino]propanoyl]amino]-N-[(2S,3S)-3-methyl-1-oxo-1-(pyridin-2-ylmethylamino)pentan-2-yl]-2-propan-2-ylhexanamide
[Molecular Formula]

C45H61N7O7
[MDL Number]

MFCD00902835
[MOL File]

112190-24-6.mol
[Molecular Weight]

812.009
Hazard InformationBack Directory
[Uses]

U 75875, is a peptidomimetic inhibitor, that inhibits HIV-1 gag-pol protein. In human peripheral blood mononuclear cells and in a continuous cell line, U-75875 completely blocked HIV replication, so it can be used as therapeutic potential of protease inhibitors for treatment of HIV infection.
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