| Identification | Back Directory | [Name]
3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE | [CAS]
112192-04-8 | [Synonyms]
Roxindole
RoxindoleHCl
Roxindole [inn]
ROXINDOLE HYDROCHLORIDE
1H-Indol-5-ol, 3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-
3-[4-(3,6-Dihydro-4-phenylpyridine-1(2H)-yl)butyl]-1H-indole-5-ol
3-[4-[(3,6-Dihydro-4-phenylpyridin)-1(2H)-yl]butyl]-1H-indol-5-ol
3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE | [Molecular Formula]
C23H26N2O | [MDL Number]
MFCD04038810 | [MOL File]
112192-04-8.mol | [Molecular Weight]
346.47 |
| Chemical Properties | Back Directory | [Melting point ]
>165°C (dec.) | [Boiling point ]
575.7±50.0 °C(Predicted) | [density ]
1.173±0.06 g/cm3(Predicted) | [storage temp. ]
Desiccate at -20°C | [solubility ]
DMSO (Slightly), Water (Slightly) | [form ]
Solid | [pka]
10.15±0.40(Predicted) | [color ]
Pale Beige to Light Beige | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
Roxindole Hydrochloride is a selective and potent presynaptic D-2 dopamine autoreceptor agonist. | [Definition]
ChEBI: Roxindole is a member of indoles. It has a role as an alpha-adrenergic antagonist and a serotonergic drug. | [Biological Activity]
Dopamine D 2 autoreceptor agonist, with affinity for D 3 , D 4 and 5-HT 1 receptors (pK i values are 8.55, 8.93, 8.23, 9.42, 6.00 and 7.05 for human D 2 , D 3 , D 4 , 5-HT 1A , 5-HT 1B and 5-HT 1D receptors). Inhibits 5-HT uptake and is antidepressant in vivo . |
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Energy Chemical
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http://www.energy-chemical.com |
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BIOTREND GmbH
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www.biotrend.de |
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Labinova AB
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