ChemicalBook--->CAS DataBase List--->1123889-87-1

1123889-87-1

1123889-87-1 Structure

1123889-87-1 Structure
IdentificationBack Directory
[Name]

XL-765,SAR245409
[CAS]

1123889-87-1
[Synonyms]

XL765
CS-432
SAR245409
XL-765,SAR245409
XL765(Voxtalisib)
XL-765,SAR245409 USP/EP/BP
N-(4-(N-(3-((3,5-DiMethoxyphenyl)aMino)quinoxalin-2-yl)sulfaMoyl)phenyl)-3-Methoxy-4-MethylbenzaMide
N-[2-[(3,5-Dimethoxyphenyl)amino]quinoxalin-3-yl]-4-[(4-methyl-3-methoxyphenyl)carbonyl]aminophenylsulfonamide
[Molecular Formula]

C31H29N5O6S
[MDL Number]

MFCD25976744
[MOL File]

1123889-87-1.mol
[Molecular Weight]

599.657
Chemical PropertiesBack Directory
[density ]

1.387
[solubility ]

Soluble in DMSO
[form ]

Powder
Hazard InformationBack Directory
[Uses]

XL765 is a low-molecular mass PI3K inhibitor that also inhibits DNA-PK and mTOR.
[Definition]

ChEBI: XL765 is a sulfonamide obtained by formal condensation of the sulfonic acid group of 4-[(3-methoxy-4-methylbenzoyl)amino]benzenesulfonic acid with the primary aromatic amino group of N-(3,5-dimethoxyphenyl)quinoxaline-2,3-diamine. A dual PI3K/mTOR inhibitor used in cancer treatment. It has a role as an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor, an antineoplastic agent and a mTOR inhibitor. It is a sulfonamide, a quinoxaline derivative, an aromatic amine, a member of benzamides and an aromatic ether.
[target]

p110α
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