| Identification | Back Directory | [Name]
OlMesartan MedoxoMil-d6 | [CAS]
1127298-67-2 | [Synonyms]
CS-866-d6
OlMetec-d6
Benicar-d6
OlMesartan MedoxoMil-d6
[2H6]-Olmesartan Medoxomil
UQGKUQLKSCSZGY-LIJFRPJRSA-N
4-[1-Hydroxy-1-(Methylethyl-d6)]-2-propyl-1-[[2'-(1H-tetazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-1H-iMidazole-5-carboxylic Acid (5-Methyl-2-oxo-1,3-dioxol-4-yl)Methyl Ester | [Molecular Formula]
C29H29N6O6 | [MOL File]
1127298-67-2.mol | [Molecular Weight]
557.577 |
| Chemical Properties | Back Directory | [Melting point ]
>75°C (dec.) | [storage temp. ]
Refrigerator | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Description]
Olmesartan medoxomil-d6 is intended for use as an internal standard for the quantification of olmesartan medoxomil by GC- or LC-MS. Olmesartan medoxomil is an orally bioavailable prodrug form of olmesartan , a nonpeptide angiotensin II antagonist that is selective for the angiotensin 1 (AT1) receptor over the AT2 receptor. Olmesartan medoxomil (0.1 mg/kg) inhibits the angiotensin II pressor response in normotensive rats. It reduces both systolic and diastolic blood pressure in fructose-fed rats, a model of insulin resistance, when administered at a dose of 10 mg/kg per day, as well as in chow-fed control animals when administered at a dose of 11.4 mg/kg per day. Olmesartan medoxomil also inhibits increases in plasma levels of triglycerides and non-esterified fatty acids in fructose-fed rats. Formulations containing olmesartan medoxomil have been used in the treatment of hypertension. | [Chemical Properties]
White to Off-White Solid | [Uses]
A labelled angiotensin II receptor antagonist. Used as an anti-hypertensive. | [Uses]
Labelled Olmesartan Medoxomil (O550000). Olmesartan Medoxomil is an angiotensin II receptor antagonist. Olmesartan Medoxomil is used as an anti-hypertensive. | [Uses]
OlMesartan MedoxoMil-d6 is an angiotensin II receptor antagonist,it is used as an anti-hypertensive.
| [storage]
Store at -20°C |
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|