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1134639-23-8

1134639-23-8 Structure

1134639-23-8 Structure
IdentificationBack Directory
[Name]

(1E,4Z,6E)-1,7-Bis[4-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-3-Methoxyphenyl]-5-hydroxy-1,4,6-heptatrien-3-one
[CAS]

1134639-23-8
[Synonyms]

Di-(tert-Butyl-diMethylsilyl) CurcuMin
(1E,4Z,6E)-1,7-BIS(4-((TERT-BUTYLDIMETHYLSILYL)OXY)-3-METHOXYPHENYL)-5-HYDROXYHEPTA-1,4,6-TRIEN-3-ONE
(1E,4Z,6E)-1,7-Bis[4-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-3-Methoxyphenyl]-5-hydroxy-1,4,6-heptatrien-3-one
1,4,6-Heptatrien-3-one, 1,7-bis[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxyphenyl]-5-hydroxy-, (1E,4Z,6E)-
[Molecular Formula]

C33H48O6Si2
[MDL Number]

MFCD28138384
[MOL File]

1134639-23-8.mol
[Molecular Weight]

596.9
Chemical PropertiesBack Directory
[Melting point ]

138-140oC
[storage temp. ]

Refrigerator
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

Yellow
Hazard InformationBack Directory
[Chemical Properties]

Yellow Solid
[Uses]

Protected Curcumin (C838500). A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.
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