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114560-48-4

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114560-48-4 Structure

114560-48-4 Structure
IdentificationBack Directory
[Name]

APAZIQUONE,1H-INDOLE-4,7-DIONE, 5-(1-AZIRIDINYL)-3-(HYDROXYMETHYL)-2-(3-HYDROXY-1-PROPENYL)-1-METHYL-, (E)-
[CAS]

114560-48-4
[Synonyms]

EO 9
NSC 382456
NSC 382459
EO 9 (pharmaceutical)
5-(1-aziridinyl)-3-(hydroxyMethyl)-2-[(E)-3-hydroxyprop-1-enyl]-1-Methyl-1H-indole-4,7-dione
5-(1-Aziridinyl)-3-(hydroxymethyl)-2-[(1E)-3-hydroxy-1-propen-1-yl]-1-methyl-1H-indole-4,7-dione
(E)-5-(aziridin-1-yl)-3-(hydroxymethyl)-2-(3-hydroxyprop-1-en-1-yl)-1-methyl-1H-indole-4,7-dione
1H-Indole-4,7-dione, 5-(1-aziridinyl)-3-(hydroxymethyl)-2-[(1E)-3-hydroxy-1-propen-1-yl]-1-methyl-
APAZIQUONE,1H-INDOLE-4,7-DIONE, 5-(1-AZIRIDINYL)-3-(HYDROXYMETHYL)-2-(3-HYDROXY-1-PROPENYL)-1-METHYL-, (E)-
[Molecular Formula]

C15H16N2O4
[MDL Number]

MFCD00876411
[MOL File]

114560-48-4.mol
[Molecular Weight]

288.301
Chemical PropertiesBack Directory
[Boiling point ]

632.3±55.0 °C(Predicted)
[density ]

1.45
[pka]

13.58±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

Apaziquone is an indolequinone that is a bioreductive prodrug and a chemical analog of Mitomycin C (M371900), a chemotherapeutic agent. Apaziquone is a potential therapeutic agent for the treatment of non-muscle invasive bladder cancer.
[Definition]

ChEBI: Apaziquone is a member of indoles.
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