| Identification | Back Directory | [Name]
PHILANTHOTOXIN 343 TRIS-TRIFLUOROACETATE | [CAS]
115976-93-7 | [Synonyms]
phtx-343
(S)-PTX 343
PhTX-343 TFA
(S)-PhTX 343
philanthotoxin 343
(S)-Philanthotoxin 343
philanthotoxin 343 tris(trifluoroacetate) salt
PHILANTHOTOXIN 343 TRIS-TRIFLUOROACETATE BLOCKS NMDA-GATED ION
N-[3-[4-(3-Aminopropylamino)butylamino]propyl]-Nα-butyryl-L-tyrosinamide
N-[3-[[4-[(3-Aminopropyl)amino]butyl]amino]propyl]-Nα-butanoyl-L-tyrosinamide
(S)-N-[3-[4-(3-Aminopropylamino)butylamino]propyl]-2-(butyrylamino)-3-(4-hydroxyphenyl)propionamide
(S)-N-[3-[[4-[(3-Aminopropyl)amino]butyl]amino]propyl]-4-hydroxy-α-[(1-oxobutyl)amino]benzenepropanamide
Benzenepropanamide, N-[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]-4-hydroxy-α-[(1-oxobutyl)amino]-, (αS)-
S-N-[3-[[4-[(3-Aminopropyl)amino]butyl]amino]propyl]-4-hydroxy-α-[(1-oxobutyl)amino]-benzenepropanamide tris-trifluoroacetate
PhTX-343, S-N-[3-[[4-[(3-Aminopropyl)amino]butyl]amino]propyl]-4-hydroxy-α-[(1-oxobutyl)amino]-benzenepropanamide tris-trifluoroacetate | [Molecular Formula]
C23H41N5O3 | [MDL Number]
MFCD00661073 | [MOL File]
115976-93-7.mol | [Molecular Weight]
435.6 |
| Chemical Properties | Back Directory | [Boiling point ]
716.9±60.0 °C(Predicted) | [density ]
1.084±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
methanol: >8 mg/mL solutions should be freshly prepared. | [form ]
solid | [pka]
9.83±0.15(Predicted) | [color ]
light yellow-green |
| Hazard Information | Back Directory | [Uses]
Philanthotoxin 343 tris(trifluoroacetate) salt has been used as Ca2+-permeable α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) blocker. It has also been used as an effective glutamate receptors blocker in an acute homeostasis paradigm to examine the speed of the Neto-α-mediated homeostatic response in Drosophila. | [Definition]
ChEBI: Philanthotoxin 343 is a N-acyl-amino acid. | [Biochem/physiol Actions]
Blocks NMDA-gated ion channels; synthetic analog of the wasp polyamine amide toxin δ-philanthotoxin. |
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