| Identification | Back Directory | [Name]
2-Bromo-6-(tetrahydrofuran-3-yl)pyridine | [CAS]
1159822-10-2 | [Synonyms]
2-bromo-6-(oxolan-3-yl)pyridine
2-Bromo-6-(tetrahydrofuran-3-yl)pyridine | [Molecular Formula]
C9H10BrNO | [MDL Number]
MFCD12033492 | [MOL File]
1159822-10-2.mol | [Molecular Weight]
228.09 |
| Hazard Information | Back Directory | [Reactions]
A mixture of 2-bromo-6-(tetrahydrofuran-3-yl)pyridine (1.24 g), TEA (661.26 mg), and Pd(dppf)Cl2 (199.23 mg) in MeOH (100 mL) was heated at 110°C for 24 hours under CO atmosphere. The reaction mixture was concentrated, and the residue was suspended in MTBE and filtered through a silica gel pad. The filtrate was evaporated to give methyl 6-(tetrahydrofuran-3-yl)picolinate (400 mg, 35.42% yield) as a reddish oil. |
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