| Identification | Back Directory | [Name]
CZC24832 | [CAS]
1159824-67-5 | [Synonyms]
CS-957
CZC24832
CZC24832 USP/EP/BP
CZC 24832;CZC-24832
5-(2-amino-8-fluoro-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-tert-butylpyridine-3-sulfonamide
5-(2-Amino-8-fluoro[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-(tert-butyl)-3-pyridinesulfonamide
5-(2-Amino-8-fluoro[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-(1,1-dimethylethyl)-3-pyridinesulfonamide
3-Pyridinesulfonamide, 5-(2-amino-8-fluoro[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-(1,1-dimethylethyl)-
CZC 24832
5-(2-Amino-8-fluoro[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-(tert-butyl)-3-pyridinesulfonamide
5-(2-Amino-8-fluoro[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-(tert-butyl)-3-pyridinesulfonamide CZC 24832 | [EINECS(EC#)]
200-258-5 | [Molecular Formula]
C15H17FN6O2S | [MDL Number]
MFCD22417090 | [MOL File]
1159824-67-5.mol | [Molecular Weight]
364.4 |
| Chemical Properties | Back Directory | [density ]
1.51 | [storage temp. ]
Store at -20°C | [solubility ]
insoluble in H2O; insoluble in EtOH; ≥6.07 mg/mL in DMSO with gentle warming | [form ]
solid | [pka]
10.29±0.50(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
CZC24832 is a selective phosphoinositide 3-kinase γ (PI3Kγ) inhibitor. CZC24832 regulates interleukin-17-producing T helper cell (TH17) differentiation by PI3Kγ thus making CZC24832 a potential treatment for inflammatory and autoimmune diseases. |
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