| Identification | Back Directory | [Name]
4-PREGNENE-17-A-20-B-21-TRIOL-*3-11-DION E | [CAS]
116-59-6 | [Synonyms]
20α-Dihydrocortisone
202-Dihydrocortisone
4-Pregnene-17α,20β,21-triol-3,11-dione
4-PREGNENE-17-A-20-B-21-TRIOL-*3-11-DION E
17α,20β,21-Trihydroxy-4-pregnene-3,11-dione
17ALPHA,20B,21-Trihydroxy-4-pregnene-3,11-dione
(20R)-17,20,21-Trihydroxypregn-4-ene-3,11-dione
17-alpha,20-beta,21-trihydroxypregn-4-ene-3,11-dione | [Molecular Formula]
C21H30O5 | [MOL File]
116-59-6.mol | [Molecular Weight]
362.46 |
| Chemical Properties | Back Directory | [Melting point ]
>82°C (dec.) | [storage temp. ]
-20°C Freezer | [solubility ]
Acetone (Slightly), Chloroform (Slightly), DMSO (Slightly), Methanol (slightly) | [form ]
Solid | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
20β-Dihydrocortisone is a metabolite of Cortisol (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism. | [Definition]
ChEBI: 20beta-hydroxycortisone is a C21-steroid that is cortisone in which the oxo group at position 20 is replaced by a hydroxy group. It has a role as a human urinary metabolite. It is a C21-steroid, a 20-hydroxy steroid, a 3-oxo-Delta(4) steroid, a 21-hydroxy steroid, a 17alpha-hydroxy steroid and an 11-oxo steroid. It is functionally related to a cortisone. It derives from a hydride of a pregnane. |
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