ChemicalBook--->CAS DataBase List--->116057-57-9

116057-57-9

116057-57-9 Structure

116057-57-9 Structure
IdentificationBack Directory
[Name]

Farnesyl Pyrophosphate Triammonium Salt
[CAS]

116057-57-9
[Synonyms]

Farensyl Pyrophosphate D3 Triammonium Salt
Farnesyl Pyrophosphate Ammonium Salt, in Ethanol DISCONTINUED. Please see F102470
(E,E)-Diphosphoric Acid Mono(3,7,11-triMethyl-2,6,10-dodecatrienyl) Ester TriaMMoniuM Salt
Diphosphoric Acid P-[(2E,6E)-3,7,11-TriMethyl-2,6,10-dodecatrien-1-yl] Ester AMMoniuM Salt
[Molecular Formula]

C15H37N3O7P2
[MDL Number]

MFCD00189688
[MOL File]

116057-57-9.mol
[Molecular Weight]

433.418
Chemical PropertiesBack Directory
[storage temp. ]

Amber Vial, -20°C Freezer, Under Inert Atmosphere
[solubility ]

Methanol:NH4OH (70:30): * 1 mg/ml
[form ]

Solid
[color ]

White to Brown
[Stability:]

Hygroscopic, Light Sensitive, Temperature Sensitive
Safety DataBack Directory
[Symbol(GHS) ]


GHS02,GHS05,GHS06,GHS08,GHS09
[Signal word ]

Danger
[Hazard statements ]

H225-H301+H311+H331-H314-H370-H400
[Precautionary statements ]

P210-P240-P241-P242-P243-P260-P264-P270-P271-P273-P280-P301+P310-P321-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P307+P311-P312-P361+P364-P370+P378-P391-P403+P233-P403+P235-P405-P501
Hazard InformationBack Directory
[Description]

Farnesyl pyrophosphate is an intermediate in the HMG-CoA reductase pathway and used in the biosynthesis of terpenes, terpenoids, and sterols. It also serves as a donor in post-translational isoprenylation of proteins. FPP has been identified as an antagonist of P2Y12 receptors (IC50 = 45 μM), attenuating platelet aggregation. It has also been shown to regulate adipocyte function as an endogenous PPARγ agonist. Additionally, because of a flexible hydrocarbon chain that enables different conformations, FPP is a promiscuous ligand for a subset of nuclear receptors.
[Chemical Properties]

Pale Yellow Low Melting Solid
[Uses]

Isoprenoid from the intracellular mevalonate pathway used for prenylation of several low molecular mass G proteins, including Ras.
[Uses]

Isoprenoid from the intracellular mevalonate pathway, Farnesyl Pyrophosphate Triammonium Salt can be used for prenylation of several low molecular mass G proteins, including Ras.
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