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116653-28-2

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116653-28-2 Structure

116653-28-2 Structure
IdentificationBack Directory
[Name]

BUSULFAN-D8 (TETRAMETHYLENE-D8)
[CAS]

116653-28-2
[Synonyms]

GT-41-d8
Myleran-d
Myleran-d8
CB-2041-d8
Misulban-d8
Busulfan-d8
Busulfex-d8
Busulphan-d8
Busulfan-D8(tetramethylene)
BUSULFAN-D8 (TETRAMETHYLENE-D8)
1,4-Butanediol-d8-dimethanesulfonate Esters
[Molecular Formula]

C6H6D8O6S2
[MDL Number]

MFCD06658695
[MOL File]

116653-28-2.mol
[Molecular Weight]

254.35
Chemical PropertiesBack Directory
[Appearance]

White Solid
[Melting point ]

112-1140C
[storage temp. ]

-20°C Freezer
[solubility ]

DMF: 16.7 mg/ml,DMSO: 16.7 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
[form ]

A crystalline solid
[color ]

White to off-white
Hazard InformationBack Directory
[Chemical Properties]

White Solid
[Uses]

Alkylating agent with antileukemic activity. Antineoplastic
[Description]

Busulfan-d8 is intended for use as an internal standard for the quantification of busulfan (Item No. 14843) by GC- or LC-MS. Busulfan is an alkyl sulfonate that acts as an alkylating antineoplastic agent. It forms both intra- and interstrand crosslinks on DNA. In mammals, busulfan causes profound and prolonged reduction in the generation of hematopoietic progenitors without significantly affecting lymphocyte levels or humoral antibody responses.
Safety DataBack Directory
[Symbol(GHS) ]


GHS06,GHS08
[Signal word ]

Danger
[Hazard statements ]

H301-H310+H330-H350
[Precautionary statements ]

P201-P202-P260-P262-P264-P270-P271-P280-P284-P301+P310-P330-P302+P352-P304+P340-P308+P313-P320-P361+P364-P403+P233-P405-P501
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