| Identification | Back Directory | [Name]
(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester | [CAS]
1168150-46-6 | [Synonyms]
(3E)-2
Nintedanib-017
BIBF1120 Intermediate4
Nintedanib Impurity 125
Nintedanib Intermediate 4
Nintedanib ethanesulfonate intermediates
oxo-1h-indole-6-carboxylic acid methyl ester
methyl (E)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester
(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl este
(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester
1H-Indole-6-carboxylic acid, 2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-, methyl ester, (3E)- | [EINECS(EC#)]
927-895-9 | [Molecular Formula]
C18H15NO4 | [MDL Number]
MFCD28139165 | [MOL File]
1168150-46-6.mol | [Molecular Weight]
309.32 |
| Chemical Properties | Back Directory | [Boiling point ]
523.8±50.0 °C(Predicted) | [density ]
1.273±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
10.62±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
(E)-Methyl 3-(Methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate is an intermediate of (E)-Intedanib [I666670]. It is also used as a reactant in the preparation of deuterated derivatives of Nintedanib (N478290), which is angiokinase inhibitor with antitumor activity. |
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