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1169766-01-1

1169766-01-1 Structure

1169766-01-1 Structure
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[Name]

Ramatercept
[CAS]

1169766-01-1
[Synonyms]

RAMATERCEPT
Research Grade Ramatercept (DHA30606)
Activin receptor type IIB (synthetic human extracellular domain fragment) fusion protein with glycylglycylglycine fusion protein with immunoglobulin G1 (synthetic human Fc region C-terminal fragment), dimer
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[Description]

Ramatercept is a soluble ActRIIB receptor and can be used as a soluble activin receptor 2 (ACVR2) antagonist. Ramatercept inhibits the signal pathway of muscle growth inhibition and has potential application in muscle atrophy.
[in vivo]

Ramatercept (10 mg/kg; s.c.; three times a week for 5 weeks) significantly increases the muscle mass of mice.
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