| Identification | Back Directory | [Name]
1-(3-mercapto-1-oxopropoxy)-2,5-pyrrolidinedione | [CAS]
117235-10-6 | [Synonyms]
3-Mercaptopropanyl-NHS ester
3-Mercaptopropionic acid NHS ester
Methanesulfonamide,N-(6-aminophenyl)-
3-Mercaptopropanyl-N-hydroxysuccinimide ester
2,5-Dioxopyrrolidin-1-yl 3-mercaptopropanoate
3-Mercapropropanoyl-N-hydroxysuccinimide ester
1-(3-mercapto-1-oxopropoxy)-2,5-pyrrolidinedione
3-Mercaptopropanyl-N-hydroxysuccinimide ester >97%
Propanoic acid, 3-mercapto-, 2,5-dioxo-1-pyrrolidinyl ester | [Molecular Formula]
C7H9NO4S | [MDL Number]
MFCD28964889 | [MOL File]
117235-10-6.mol | [Molecular Weight]
203.22 |
| Chemical Properties | Back Directory | [Boiling point ]
318.4±44.0 °C(Predicted) | [density ]
1.40±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [form ]
Liquid | [pka]
9.42±0.10(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Uses]
3-Mercaptopropanyl-N-hydroxysuccinimide ester is an aliphatic, heterobifunctional crosslinking reagent. Due to the functional groups, this material can be used in a multitude of applications, such as the synthesis of protien-polymer conjugates and the synthesis of functionalized quantum dots. In addition to use as a crosslinking agent, this material can also be used to install functional groups post-polymerization. The terminal N-hydroxysuccinimide (NHS) ester can react with amines while the terminal thiol can react with thiols, alkenes, and alkynes. The free thiol can also be used to form self-assembled monolayers (SAMs) on gold surfaces. |
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