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1173023-51-2

1173023-51-2 Structure

1173023-51-2 Structure
IdentificationBack Directory
[Name]

Bufuralol-(t-butyl-d9) hydrochloride
[CAS]

1173023-51-2
[Synonyms]

2H9]-Bufuralol
Bufuralol hydrochloride salt
[2H9]-Bufuralol Hydrochloride
2H9]-Bufuralol hydrochloride salt
Bufuralol-(t-butyl-d9) hydrochloride
[Molecular Formula]

C16H24ClNO2
[MDL Number]

MFCD09840134
[MOL File]

1173023-51-2.mol
[Molecular Weight]

297.82
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Methanol: slightly soluble
[form ]

A solid
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Precautionary statements ]

P264-P270-P301+P312-P330-P501
[Hazard Codes ]

Xn
[Risk Statements ]

22
Hazard InformationBack Directory
[Description]

Bufuralol-d9 is intended for use as an internal standard for the quantification of bufuralol by GC- or LC-MS. Bufuralol is a non-selective antagonist of β-adrenergic receptors (β-ARs) that also has partial agonist activity. It decreases mean arterial blood pressure and increases abdominal aortic blood flow in anesthetized cats when administered intravenously at doses of 0.3 and 1 mg/kg. Bufuralol is hydroxylated at the 1'' position by the cytochrome P450 (CYP) isoform CYP2D6 and has been used as a substrate to measure CYP2D6 activity.
[Uses]

A b-Adrenergic blocker with peripheral vasodilating activity. Antianginal
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