Identification | Back Directory | [Name]
Bufuralol-(t-butyl-d9) hydrochloride
| [CAS]
1173023-51-2 | [Synonyms]
2H9]-Bufuralol Bufuralol hydrochloride salt [2H9]-Bufuralol Hydrochloride 2H9]-Bufuralol hydrochloride salt Bufuralol-(t-butyl-d9) hydrochloride
| [Molecular Formula]
C16H24ClNO2 | [MDL Number]
MFCD09840134 | [MOL File]
1173023-51-2.mol | [Molecular Weight]
297.82 |
Hazard Information | Back Directory | [Description]
Bufuralol-d9 is intended for use as an internal standard for the quantification of bufuralol by GC- or LC-MS. Bufuralol is a non-selective antagonist of β-adrenergic receptors (β-ARs) that also has partial agonist activity. It decreases mean arterial blood pressure and increases abdominal aortic blood flow in anesthetized cats when administered intravenously at doses of 0.3 and 1 mg/kg. Bufuralol is hydroxylated at the 1'' position by the cytochrome P450 (CYP) isoform CYP2D6 and has been used as a substrate to measure CYP2D6 activity. | [Uses]
A b-Adrenergic blocker with peripheral vasodilating activity. Antianginal |
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Company Name: |
Energy Chemical
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Tel: |
021-58432009 400-005-6266 |
Website: |
http://www.energy-chemical.com |
Company Name: |
Pharma Affiliates
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Tel: |
172-5066494 |
Website: |
https://www.chemicalbook.com/ShowSupplierProductsList694812/0.htm |
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