ChemicalBook--->CAS DataBase List--->1183-35-3

1183-35-3

1183-35-3 Structure

1183-35-3 Structure
IdentificationBack Directory
[Name]

DIHYDROOUABAIN
[CAS]

1183-35-3
[Synonyms]

dihydroouabin
DIHYDROOUABAIN
DIHYDROOUABAIN(RG)
Dihydro-g-strophatin
dihydro-g-strophathin
DIHYDRO-G-STROPHANTHIN
,11-alpha,14,19-pentahydroxy-
5-beta-20-xi-cardanolide,3-beta-((6-deoxy-alpha-l-mannopyranosyl)oxy)-1-beta,5
(20ξ)-3β-[(6-Deoxy-α-L-mannopyranosyl)oxy]-1β,5,11α,14,19-pentahydroxy-5β-cardanolide
Cardanolide, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxy-, (1β,3β,5β,11α,20ξ)-
(20xi)-3beta-[(6-deoxy-alpha-L-mannopyranosyl)oxy]-1beta,5beta,11alpha,14,19-pentahydroxycardanolide
[EINECS(EC#)]

214-663-0
[Molecular Formula]

C29H46O12
[MDL Number]

MFCD00049227
[MOL File]

1183-35-3.mol
[Molecular Weight]

586.67
Chemical PropertiesBack Directory
[Melting point ]

168-170 °C
[Boiling point ]

827.7±65.0 °C(Predicted)
[density ]

1.49±0.1 g/cm3(Predicted)
[pka]

13.04±0.70(Predicted)
Safety DataBack Directory
[Hazard Codes ]

T
[Risk Statements ]

23/24/25
[Safety Statements ]

36/37/39-45
[RIDADR ]

1544
[WGK Germany ]

3
[RTECS ]

FH4551000
[HazardClass ]

6.1(b)
[PackingGroup ]

III
[Toxicity]

LD50 intravenous in cat: 370mg/kg
Hazard InformationBack Directory
[Uses]

Dihydroouabain is a cardiac glycoside, a natural product found to be effective against various cancer cells. An inotropic drug and an inhibitor of sodium-potassium pump.
[Definition]

ChEBI:Dihydroouabain is a cardenolide glycoside that is ouabain in which the double bond in the lactone ring has been reduced to a single bond. It is a cardiac glycoside and a derivative of ouabain which is used as a sodium pump antagonist and exhibits ionotropic effects. It has a role as a radiosensitizing agent and an EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor. It is functionally related to an ouabain.
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