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1187230-70-1

1187230-70-1 Structure

1187230-70-1 Structure
IdentificationBack Directory
[Name]

Crisaborole intermediate
[CAS]

1187230-70-1
[Synonyms]

Crisaborole Impurity 34
5-(4-(aminomethyl)phenoxy)benzo[c][1,2]oxaborol-1(3H)-ol
Benzenemethanamine, 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-
4-?[(1,?3-?Dihydro-?1-?hydroxy-?2,?1-?benzoxaborol-?5-?yl)?oxy]?-benzenemethanamine
[Molecular Formula]

C14H14BNO3
[MOL File]

1187230-70-1.mol
[Molecular Weight]

255.08
Chemical PropertiesBack Directory
[Boiling point ]

417.2±55.0 °C(Predicted)
[density ]

1.28±0.1 g/cm3(Predicted)
[pka]

7.04±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

4-?[(1,?3-?Dihydro-?1-?hydroxy-?2,?1-?benzoxaborol-?5-?yl)?oxy]?-benzenemethanamine is used as a research tool in the assessment of its benzoxaborole moiety to serve as a hinge-binding scaffold for ROCK inhibition; playing a role in SMC relaxation in rat aorta and guinea pig trachea.
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