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1187479-72-6

1187479-72-6 Structure

1187479-72-6 Structure
IdentificationBack Directory
[Name]

(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate
[CAS]

1187479-72-6
[Synonyms]

Bortezomib Impurity 53
(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate
tert-butyl 4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)-benzoyl)piperazin-1-carboxylate
[Molecular Formula]

C29H45BN2O5
[MDL Number]

MFCD18207137
[MOL File]

1187479-72-6.mol
[Molecular Weight]

512.49
Hazard InformationBack Directory
[Uses]

N-[(1S)-2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-Carbamic Acid 1,1-Dimethylethyl Ester is an intermediate in the synthesis of bortezomib (B675700).Bortezomib is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer.
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