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1189423-58-2

1189423-58-2 Structure

1189423-58-2 Structure
IdentificationBack Directory
[Name]

5-fluoro-1H-pyrimidine-2,4-dione
[CAS]

1189423-58-2
[Synonyms]

[13C,15N2]-5-Fluorouracil
[Molecular Formula]

C4H3FN2O2
[MDL Number]

MFCD09840633
[MOL File]

1189423-58-2.mol
[Molecular Weight]

130.077
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: slightly soluble; Methanol: slightly soluble
[form ]

A solid
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS06
[Signal word ]

Danger
[Hazard statements ]

H301
[Precautionary statements ]

P264-P270-P301+P310-P321-P330-P405-P501
Hazard InformationBack Directory
[Description]

5-Fluorouracil-13C,15N2 is intended for use as an internal standard for the quantification of 5-flurouracil by GC- or LC-MS. 5-Fluorouracil is a pyrimidine analog that irreversibly inhibits thymidylate synthase, blocking the synthesis of thymidine which is required for DNA synthesis. Intracellular metabolites of 5-fluorouracil exert cytotoxic effects by either inhibiting thymidylate synthetase, or through incorporation into RNA and DNA, ultimately initiating apoptosis.
[Uses]

Labelled 5-FU, a potent antineoplastic agent in clinical use. Also an inhibitor of DNA synthesis.
[storage]

Store at -20°C
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