| Identification | Back Directory | [Name]
Trimethoprim-d3 | [CAS]
1189923-38-3 | [Synonyms]
Tiempe-d3
Uretrim-d3
Instalac-d3
Monotrim-d3
Trimanyl-d3
Syraprim-d3
Proloprim-d3
Wellcoprim-d3
Trimethoprim-d3
[2H3]-Trimethoprim
Trimethoprim-d3 (Major)
5-[(3,4,5-TriMethoxy-d3-phenyl)Methyl]-
2,4-Diamino-5-(3',4',5'-trimethoxy-d3-benzyl)pyrimidine
5-[(3,4,5-Trimethoxy-d3-phenyl)methyl]-2,4-pyrimidinediamine
5-[[3,5-dimethoxy-4-(trideuteriomethoxy)phenyl]methyl]pyrimidine-2,4-diamine | [Molecular Formula]
C14H18N4O3 | [MDL Number]
MFCD16039497 | [MOL File]
1189923-38-3.mol | [Molecular Weight]
290.318 |
| Chemical Properties | Back Directory | [Melting point ]
208-210°C | [storage temp. ]
Hygroscopic, -20°C Freezer, Under Inert Atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
White to Pale Yellow |
| Hazard Information | Back Directory | [Description]
Trimethoprim-d3 is intended for use as an internal standard for the quantification of trimethoprim by GC- or LC-MS. Trimethoprim is a synthetic antibiotic that inhibits dihydrofolate reductase (DHFR), which is necessary for the synthesis of purines, amino acids, and thymidylic acid. Trimethoprim shows prominent selectivity for bacterial DHFR over mammalian DHFR (IC50s = 5 and 30,000 nM, respectively). Formulations containing trimethoprim, commonly used in combination with sulfamethoxazole to minimize acquired resistance, have been used in the treatment of urinary tract infections. | [Chemical Properties]
Off-White to Pale Yellow Solid | [Uses]
Deuterated Trimethoprim, an antibacterial | [Uses]
Trimethoprim-d3 (Major) is an antibacterial. |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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