| Identification | Back Directory | [Name]
2,2,2-trifluoroacetic acid | [CAS]
120103-89-1 | [Synonyms]
(2S)-2-[[2-[[(2S)-2-Amino-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]butanedioic acid | [Molecular Formula]
C14H23F3N6O8 | [MDL Number]
MFCD31619303 | [MOL File]
120103-89-1.mol | [Molecular Weight]
460.37 |
| Hazard Information | Back Directory | [Biological Activity]
Arg-Gly-Asp (RGD) is a synthetic peptide corresponding to the cell adhesion sequence for the integrins αVβ1, αVβ3, αVβ5, αVβ6, αVβ8, α8β1, and α5β1.1,2 It is a component of radioligands and peptidomimetics that have been used in the study of integrin expression and activity in vivo.2,3 | [References]
1.Ruoslahti, E.RGD and other recognition sequences for integrinsAnnu. Rev. Cell Dev. Biol.12697-715(1996)
2.Danhier, F., Le Breton, A., and Préat, V.RGD-based strategies to target alpha(v) beta(3) integrin in cancer therapy and diagnosisMol. Pharm.9(11)2961-2973(2012)
3.Schottelius, M., Laufer, B., Kessler, H., et al.Ligands for mapping αvβ3-integrin expression in vivoAcc. Chem. Res.42(7)969-980(2009)
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| Company Name: |
A.J Chemicals
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| Tel: |
91-9810153283 |
| Website: |
www.ajchemicals.com |
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