| Identification | Back Directory | [Name]
3-Azetidinecarboxylic acid, 1-[[3-fluoro-4-[5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridin-2-yl]phenyl]Methyl]- | [CAS]
1202073-26-4 | [Synonyms]
AMG 369
KB74649
KB-74649
KB 74649
KCMALGDZUKTGJR-UHFFFAOYSA-N
3-Azetidinecarboxylic acid, 1-[[3-fluoro-4-[5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridin-2-yl]phenyl]Methyl]- | [Molecular Formula]
C26H22FN3O2S | [MDL Number]
MFCD32645410 | [MOL File]
1202073-26-4.mol | [Molecular Weight]
459.54 |
| Hazard Information | Back Directory | [Description]
AMG-369, also known as KB74649, is a potent dual S1P1/S1P5 agonist with limited activity at S1P3 and no activity at S1P2/S1P4. Dosed orally at 0.1 mg/kg, AMG-369 is shown to reduce blood lymphocyte counts 24 h postdose and delay the onset and reduce the severity of experimental autoimmune encephalomyelitis in rat. |
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| Company Name: |
BOC Sciences
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| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
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