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1202235-68-4

1202235-68-4 Structure

1202235-68-4 Structure
IdentificationBack Directory
[Name]

BI 167107 (BI167107)
[CAS]

1202235-68-4
[Synonyms]

BI-167107
BI 167107 (BI167107)
5-hydroxy-8-(1-hydroxy-2-((2-methyl-1-(o-tolyl)propan-2-yl)amino)ethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
2H-1,4-Benzoxazin-3(4H)-one, 8-[2-[[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino]-1-hydroxyethyl]-5-hydroxy-
[Molecular Formula]

C21H26N2O4
[MOL File]

1202235-68-4.mol
[Molecular Weight]

370.44
Chemical PropertiesBack Directory
[Boiling point ]

621.7±55.0 °C(Predicted)
[density ]

1.229±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: 75 mg/mL (202.46 mM)
[form ]

Solid
[pka]

8.52±0.20(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Biological Activity]

BI-167107 is a high affinity β2 adrenergic receptor (β2AR) full agonist that binds to the β2 adrenergic receptor (β2AR) with a dissociation constant Kd of 84 pM.
[in vitro]

Compared to other βAR ligands, BI-167107 displays nanomolar affinities and slow off-rates.

[target]

Kd: 84 pM (β2AR)

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