| Identification | Back Directory | [Name]
myxochelin A | [CAS]
120243-02-9 | [Synonyms]
myxochelin A
Benzamide, N,N'-[(1S)-1-(hydroxymethyl)-1,5-pentanediyl]bis[2,3-dihydroxy- | [Molecular Formula]
C20H24N2O7 | [MOL File]
120243-02-9.mol | [Molecular Weight]
404.41 |
| Hazard Information | Back Directory | [Description]
Myxochelin A is a microbial metabolite that has been found in A. disciformis and has diverse biological activities. It is active against Gram-positive bacteria, including B. cereus, S. aureus, and M. luteus, but not Gram-negative bacteria or fungi in an agar diffusion assay when used at a concentration of 80 μg/disc. Myxochelin A inhibits 5-lipoxygenase (5-LO) activity with an IC50 value of 1.9 μM for the recombinant human enzyme. It is cytotoxic to 26-L5 colon cancer cells when used at a concentration of 3 μg/ml. | [Uses]
Myxochelin A is a potent inhibitor of human 5-lipoxygenase (5-LO). Studies show that Myxochelin A is a natural product that may possess potent antitumor activity at non-cytotoxic concentrations. |
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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