| Identification | Back Directory | [Name]
celgosivir | [CAS]
121104-96-9 | [Synonyms]
BuCast
MX3253
MBI 3253
MDL 28574
celgosivir
Celgosivir (free base)
6-O-butyl castanospermine
6-Butyryl castanospermine
Castanospermine 6-butyrate
MDL28574;MDL-28574;MDL 28574
(1S)-1,2,3,5,6,7,8,8aα-Octahydro-6α-butyryloxyindolizine-1β,7β,8α-triol
Butanoic acid, (1S,6S,7S,8R,8aR)-octahydro-1,7,8-trihydroxy-6-indolizinyl ester | [Molecular Formula]
C12H21NO5 | [MDL Number]
MFCD00886617 | [MOL File]
121104-96-9.mol | [Molecular Weight]
259.3 |
| Chemical Properties | Back Directory | [Melting point ]
114-115 °C | [Boiling point ]
422.9±45.0 °C(Predicted) | [density ]
1.33±0.1 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
Chloroform (Slightly), DMSO (Slightly) | [form ]
Solid | [pka]
13.14±0.70(Predicted) | [color ]
White to Pale Beige | [Water Solubility ]
H2O: 2mg/mL, clear | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
Antiviral; inhibitor ( α-glucosidase). | [Biological Activity]
Celgosivir is a prodrug of natural bicyclic iminosugar castanospermine th at exhibits antiviral activity in vivo including HCV and dengue. Celgosivir is an inhibitor of α-glucosidaseswhich inhibits glycoprotein processing in cell culture. Apparently inhibition of α-glucosidases within infected cell prevents secretion of virus. |
|
| Company Name: |
LGM Pharma
|
| Tel: |
1-(800)-881-8210 |
| Website: |
www.lgmpharma.com |
| Company Name: |
SPIRO PHARMA
|
| Tel: |
|
| Website: |
www.spiropharma.com.cn |
| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|