| Identification | Back Directory | [Name]
Isoderrone | [CAS]
121747-89-5 | [Synonyms]
Isoderrone
5,7-dihydroxy-2',2'-dimethyl-2'H,4H-[3,6'-bichromen]-4-one
3-(2,2-Dimethyl-2H-1-benzopyran-6-yl)-5,7-dihydroxy-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 3-(2,2-dimethyl-2H-1-benzopyran-6-yl)-5,7-dihydroxy- | [Molecular Formula]
C20H16O5 | [MDL Number]
MFCD28100649 | [MOL File]
121747-89-5.mol | [Molecular Weight]
336.34 |
| Hazard Information | Back Directory | [Description]
Isoderrone is a protein tyrosine phosphatase 1B (PTP1B) inhibitor, with IC50 value of 27 ± 7 uM, suggests that it may be a new drug for treatment of type 2 diabetes.
Isoderrone shows inhibitory effects on α-glucosidase in vitro. | [Definition]
ChEBI: Isoderrone is a hydroxyisoflavone that is isoflavone substituted by hydroxy groups at positions 5 and 7 and a 6,6-dimethyl-3,6-dihydro-2H-pyran across positions 3' and 4' respectively. It has been isolated from Ficus mucuso. It has a role as a plant metabolite. It is functionally related to an isoflavone. | [target]
Tyrosinase |
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