| Identification | Back Directory | [Name]
Flupyrazofos | [CAS]
122431-24-7 | [Synonyms]
flupyrazofos
O,O-Diethyl O-1-phenyl-3-trifluoro methylpyrazol-5-ylphosphorothioate
diethoxy-[2-phenyl-5-(trifluoromethyl)pyrazol-3-yl]oxy-sulfanylidene-$l^{5}-phosphane
Phosphorothioic acid, O,O-diethyl O-[1-phenyl-3-(trifluoromethyl)-1H-pyrazol-5-yl] ester | [Molecular Formula]
C14H16F3N2O3PS | [MDL Number]
MFCD04113183 | [MOL File]
122431-24-7.mol | [Molecular Weight]
380.32 |
| Chemical Properties | Back Directory | [Boiling point ]
399.0±52.0 °C(Predicted) | [density ]
1.37±0.1 g/cm3(Predicted) | [vapor pressure ]
3.7 x 10-3 Pa (25 °C) | [pka]
-4.99±0.10(Predicted) | [Water Solubility ]
0.8 mg l-1 (25 °C) |
| Hazard Information | Back Directory | [Description]
Water solubility of flupyrazofos is 0.8 mg/L. Log
Kow = 5.24. Flupyrazofos is slowly hydrolyzed in aqueous
media; DT50 at pH 4, 7, and 9 are 266, 180, and
121 h, respectively. Vp 3.7 mPa (25 ?C). Flupyrazofos is
a nonsystemic insecticide used for the control of caterpillars,
especially diamondblack moth, Plutella xylostella,
larvae. | [Uses]
Flupyrazofos is a new insecticide under development which has
shown good activity against caterpillars, especially Plutella xylostella
larvae. | [Uses]
Flupyrazofos is a new pyrazole organophosporus insecticide, which has a high activity against the diamond-back moth (Plutella xylostella). | [Metabolic pathway]
The principal route of metabolism of flupyrazofos is by oxidative
desulfuration to the oxon which is hydrolysed, principally via base rather
than esterase catalysis, to 1-phenyl-3-trifluoromethyl-5-hydroxypyrazole.
The physico-chemical parameters of flupyrazofos, including water solubility,
hydrolysis rates, vapour pressure and octanol/water partition
coefficients, have been reported by Kim et al. (1997). | [Metabolism]
The principal
route of metabolism of flupyrazofos is by oxidative
desulfuration to the oxon, followed by hydrolysis to 1-
phenyl-3-trifluoromethyl-5-hydroxypyrazole and diethyl
hydrogen phosphate. Flupyrazofos is degraded in soil with
DT50 of about 14 d. | [Degradation]
The hydrolytic half-life at pH values 4, 7 and 9 was 266, 180 and 121
hours, respectively (Kim et al., 1997). Flupyrazofos showed good photostability.
The photodegradation products which were identified were
flupyrazofos oxon (2), 1-phenyl-3-trifluoromethyl-5-hydroxypyrazole
(3) and the thiono-thiolo rearranged isomer O,S-diethyl O-(1-phenyl-3-
trifluoromethyl)pyrazol-5-yl phosphorothioate (4) (Cho et al., 1993) (Scheme 1). | [Toxicity evaluation]
Acute oral LD50 for rats is 372–605 mg/kg. |
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Energy Chemical
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021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
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