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122576-55-0

122576-55-0 Structure

122576-55-0 Structure
IdentificationBack Directory
[Name]

9-DEOXY-9-METHYLENE-16,16-DIMETHYL PROSTAGLANDIN E2, POTASSIUM SALT
[CAS]

122576-55-0
[Synonyms]

U-46785B
METENPROST POTASSIUM
AWJFDDHQLBRQDS-PWOMVKEHSA-N
9-DEOXY-9-METHYLENE-16,16-DIMETHYL PROSTAGLANDIN E2, POTASSIUM SALT
9-METHYLENE-11ALPHA,15R-DIHYDROXY-16,16-DIMETHYL-PROSTA-5Z,13E-DIEN-1-OIC ACID, POTASSIUM SALT
11,15-Dihydroxy-16,16-dimethyl-9-methyleneprosta-5,13-dien-1-oic acid monopotassium salt, (5Z,11alpha,13E,15R)-
Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-16,16-dimethyl-9-methylene-, monopotassium salt, (5Z,11alpha,13E,15R)-
[Molecular Formula]

C23H39KO4
[MDL Number]

MFCD01632737
[MOL File]

122576-55-0.mol
[Molecular Weight]

418.66
Chemical PropertiesBack Directory
[solubility ]

DMF: >2 mg/ml; DMSO: >12.5 mg/ml; Ethanol: >50 mg/ml; PBS pH 7.2: >50 mg/ml
[form ]

A crystalline solid
Safety DataBack Directory
[Symbol(GHS) ]


GHS07,GHS08
[Signal word ]

Danger
[Hazard statements ]

H302-H360
[Precautionary statements ]

P201-P202-P264-P270-P280-P301+P312-P330-P308+P313-P405-P501
Hazard InformationBack Directory
[Uses]

9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (metenprost) is a potent analog of PGE2 with an extended half-life in vivo. In combination with various other PG derivatives, metenprost results in the termination of first trimester pregnancy in monkeys. A single intramuscular injection containing 0.5 mg of metenprost and 7.5 mg of 17-phenyl trinor PGF1α is very effective in terminating early pregnancy. This PG mixture is ineffective on monkeys in their third trimester of pregnancy. Metenprost, when compared to PGE2 and PGF1α, in monkey and rat, does not result in unwanted side effects such as fever or gastrointestinal problems.
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