| Identification | Back Directory | [Name]
(6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE | [CAS]
1227675-51-5 | [Synonyms]
SCH 39166 HYDROBROMIDE
(6AS-TRANS)-11-CHLORO-6,6A,7,8,9,13B-HEXAHYDRO-7-METHYL-5H-BENZO[D]NAPHTH[2,1-B]AZEPIN-12-OL HYDROBROMIDE | [Molecular Formula]
C19H21BrClNO | [MDL Number]
MFCD08703109 | [MOL File]
1227675-51-5.mol | [Molecular Weight]
394.74 |
| Chemical Properties | Back Directory | [storage temp. ]
Desiccate at RT | [solubility ]
DMSO: Slightly Soluble; Methanol: Slightly Soluble; Water: Slightly Soluble | [form ]
A solid | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Description]
SCH 39166 is a dopamine D1 receptor antagonist (Ki = 5 nM). It is selective for D1 over D2-4 receptors (Kis = 3,751, >1,000, and 5,934 nM, respectively), however, it also binds to D5 receptors (Ki = 4.4 nM). SCH 39166 inhibits food intake in a dose-dependent manner in rats (ED50 = 0.84 mg/kg). It reduces ethanol intake in Sardinian alcohol-preferring rats and sucrose intake in water-deprived and water-sated rats without affecting food or total fluid intake. SCH 39166 also suppresses cocaine-induced arrhythmias in anesthetized dogs. | [Uses]
SCH 39166 is a dopamine D1/D5 receptor antagonist used in the treatment of schizophrenia, cocaine addiction and obesity. | [storage]
Desiccate at RT |
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BOC Sciences
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https://www.bocsci.com |
| Company Name: |
Energy Chemical
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021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
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