| Identification | Back Directory | [Name]
(+)-trans-Tramadol free base | [CAS]
123154-38-1 | [Synonyms]
(1R-cis)-
(+)-Tramadol
(R,R)-tramadol
(+)-trans-Tramadol free base
Cyclohexanol, 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)-, (1R,2R)- | [Molecular Formula]
C16H25NO2 | [MOL File]
123154-38-1.mol | [Molecular Weight]
263.38 |
| Hazard Information | Back Directory | [Chemical Properties]
(+)-trans-Tramadol free base is Light Yellow Oil
| [Uses]
(+)-trans-Tramadol free base is an analgesic. Used in the treatment of urinary incontinence.
| [Definition]
ChEBI: (R,R)-tramadol is a 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol in which both stereocentres have R-configuration; the (R,R)-enantiomer of the racemic opioid analgesic tramadol, it exhibits ten-fold higher analgesic potency than the (S,S)-enantiomer. It has a role as a delta-opioid receptor agonist, a kappa-opioid receptor agonist, a mu-opioid receptor agonist, an adrenergic uptake inhibitor, an antitussive, a capsaicin receptor antagonist, a muscarinic antagonist, a nicotinic antagonist, a NMDA receptor antagonist, an opioid analgesic, a serotonergic antagonist, a serotonin uptake inhibitor and a metabolite. It is a conjugate base of a (R,R)-tramadol(1+). It is an enantiomer of a (S,S)-tramadol. |
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