| Identification | Back Directory | [Name]
Naringenin-7-O-glucuronide | [CAS]
1237479-07-0 | [Synonyms]
β-D-Glucopyranosiduronic acid, 3,4-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-2H-1-benzopyran-7-yl | [Molecular Formula]
C21H20O11 | [MDL Number]
MFCD28899229 | [MOL File]
1237479-07-0.mol | [Molecular Weight]
448.38 |
| Hazard Information | Back Directory | [Description]
Naringenin-7-O-β-D-glucuronide is a metabolite of the flavonoid naringenin .1 It is formed from naringenin primarily by the UDP-glucuronosyltransferase (UGT) isoforms UGT1A1, UGT1A3, UGT1A6, and UGT1A9.2 | [References]
1. Pereira-Caro, G., Borges, G., van der Hooft, J., et al. Orange juice (poly)phenols are highly bioavailable in humans Am. J. Clin. Nutr. 100(5),1378-1384(2014).
2. Robotham, S.A., and Brodbelt, J.S. Identification of flavone glucuronide isomers by metal complexation and tandem mass spectrometry: Regioselectivity of uridine 5'-diphosphate-glucuronosyltransferase isozymes in the biotransformation of flavones J. Agric. Food Chem. 61(7),1457-1463(2013). |
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