| Identification | Back Directory | [Name]
Butanoic acid, 4,4'-(carbonyldiimino)bis-, 1,1'-bis(2,5-dioxo-1-pyrrolidinyl) ester | [CAS]
1240387-33-0 | [Synonyms]
Urea-crosslinker C4-succinimide
Urea crosslinker – C?-arm, NHS ester (DSBU, BuUrBU)
bis(2,5-dioxopyrrolidin-1-yl)4,4'-(carbonylbis(azanediyl))dibutyrate
Butanoic acid, 4,4'-(carbonyldiimino)bis-, 1,1'-bis(2,5-dioxo-1-pyrrolidinyl) ester
Butanoic acid, 4,4'-(carbonyldiimino)bis-, 1,1'-bis(2,5-dioxo-1-pyrrolidinyl) ester | [Molecular Formula]
C17H22N4O9 | [MDL Number]
MFCD30738322 | [MOL File]
1240387-33-0.mol | [Molecular Weight]
426.38 |
| Hazard Information | Back Directory | [Uses]
The ureido-4,4′-dibutyric acid bis(hydroxysuccinimide) ester, also known as DSBU or BuUrBU, is the longest version of MS-cleavable urea-based lysine-lysine reactive homobifunctional cross-linkers, featuring a C4-arm. At neutral or slightly basic pH, it irreversibly crosslinks the neighbouring lysine groups. The presence of the symmetrical urea moiety which is prone to collision-induced dissociation allows for the unambiguous distinguishing of crosslinks in tandem CID-MS experiments. | [reaction suitability]
reaction type: C-C Bond Formation
reagent type: cross-linking reagent |
|
|